Friday Nov 06, 2020

#134 Dr. Kat Arney on Cancer Evolution

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Dr. Kat Arney is our guest in this episode of DNA Today. She is a fellow genetics podcaster! She is an award-winning science writer, author, presenter, broadcaster, and public speaker. Her voice will probably be familiar to you as she has appeared on radio and TV around the world including BBC Radio 4, the Naked Scientists and Naked Genetics podcasts, and more recently as the host of the Genetics Unzipped podcast. She has written for outlets including the Times Educational Supplement, BBC Science Focus, the Daily Mail, Wired, BBC Online, The Guardian, and New Scientist. Dr. Arney has authored three popular science books: “Herding Hemingway’s Cats: Understanding How Our Genes Work”, “How to Code a Human” and her new book, “Rebel Cell: Cancer, Evolution, and the New Science of Life's Oldest Betrayal”. Enter our giveaway to win a copy of the book on our Twitter, Instagram, and Facebook.


On This Episode We Discuss:

Cancer from an evolutionary lens

Evolutionary origins of cancer at the start of multicellular life

Cancer identified through DNA from fossilized skeletons

Cancer in other species, species without cancer

Correlations between cancer development and species relationship

Conservation of cancer genes

Peter Nowell’s 40 year old paper, “The Clonal Evolution of Tumor Cell Populations”

Definition of a cancerous cell

EV-001 reveals the complexity of cancer development

Overestimate of of cancer after the development of Gleevec

Cancer evolutionary perspective adding in precision medicine


Search “Genetics Unzipped” in your podcast player to hear Dr. Arney’s show. This is a crossover episode as our host Kira Dineen, was also a guest on Genetics Unzipped in September, where she was interviewed about prenatal genetic counseling. Check out the episode titled, “Podcast Rare Genetic Disorder and Pregnancy—Navigating an ’Emotionally Challenging’ Journey.


Learn more about the book at RebelCellBook.com and keep up with Kat on Twitter, @Kat_Arney and @geneticsunzip.


In 2016, Elizabeth Turner saw a need to increase access to genetic counseling. This was the inspiration for her to start Advanced Tele-Genetic Counseling. Now during a pandemic there has never been a better time to book a telehealth genetic counseling consult! Cancer genetics is one of many areas that AT-GC specializes in. Their team of genetic counselors are specifically trained to help understand, interpret, and navigate complex genomic information. All genomes have a story to tell. If you are ready to learn yours head over to AT-GC.com to book your appointment with a genetic counselor today.


We receive a lot of emails from listeners interested in genetic careers and we love connecting and providing resources. One of those is Keck Graduate Institute’s genetics programs in Southern California. KGI offers a master’s degree in genetic counseling, but for those of you looking for something slightly different - KGI also has a first-of-its-kind graduate program in genomic data analytics. This two-year master’s program gives students the opportunity to work side-by-side with applied life scientists and future genetic counselors while gaining hands-on experience with the technologies and information that are revolutionizing the future of medicine. Learn more about the program by visiting kgi.edu/dnatoday.


Stay tuned for the next new episodes of DNA Today released on the first and third Friday of the month. In the meantime, you can listen to over 130 other episodes on Apple Podcasts, Spotify, streaming on the website, or any other podcast player by searching, “DNA Today”.


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